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KMID : 0359920110300040399
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Korean Journal of Nephrology
2011 Volume.30 No. 4 p.399 ~ p.403
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A Case of Minimal Change Nephrotic Syndrome Presented as Portal Vein Thrombosis and Acute Renal Failure
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Kwon Hee-Seon
Shin Ah-Young
Lee Hwa-Young
Cho Sung-Yeon
Kim Min-Ju
Yun Yu-Seon
Kim Hyun-Gyung
Kim Young-Soo
Choi Yeong-Jin
Kim Young-Ok
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Abstract
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Patients with the nephrotic syndrome are at risk of developing thromboembolic complications. Much evidence suggests that a hypercoagulable state exists in the setting of the nephrotic syndrome, but the exact mechanisms are poorly understood. The nephrotic syndrome associated with portal vein thrombosis is relatively uncommon. We experienced a case of minimal change nephrotic syndrome presented as portal vein thrombosis and acute renal failure. On renal biopsy, electron microscopic examination reveals diffuse foot process effacement. Treatment with corticosteroid and anticoagulation resulted in complete remission of proteinuria.
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KEYWORD
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Minimal change nephrotic syndrome, Portal vein, Thrombosis, Acute kidney injury
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